Chicken Alfredo Biscuit Casserole.”

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This savory Chicken and Biscuit Casserole recipe includes everything you need for a hearty dinner! The ultimate comfort food, with tender chicken, broccoli, cheese, and herbed biscuits.

Taking a scoop of chicken and biscuit casserole with a wooden spoon.

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Featuring the flavors of chicken alfredo, this biscuits casserole is packed with filling and satisfying ingredients for a family favorite meal that you’ll make again and again.

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Why You’ll Love This Recipe

Packed with Amazing Flavors: Featuring a cheesy and perfectly seasoned base and topped with cheddar bay biscuits, this dish delivers on flavor every time.

Great for Using Leftovers: If you have leftover chicken, this dish is a great way to turn it into a brand new, delicious meal!

Goes a Long Way: Because of how hearty and filling it is, this casserole is great for feeding the whole family and still having leftovers!

For even more amazing biscuit recipes, try my Skillet Chicken and Biscuit Pot Pie or these Bacon Egg and Cheese Biscuit Sandwiches!

Ingredients Needed

  • Garlic: Fresh garlic works best here, but jarred minced garlic can be helpful and convenient in a pinch.
  • Half and Half: Ensures that your casserole is rich and creamy.
  • Seasonings: Thanks to nutmeg, garlic powder, Italian seasoning, and salt and black pepper, this casserole is so flavorful.
  • Cheese: Using a blend of mozzarella cheese, cheddar cheese, and Parmesan cheese ensures that your casserole is incredibly cheesy and satisfying!
  • Cooked Chicken: Using leftover chicken or a rotisserie chicken from the store is a great way to add some protein to this dish.
  • Broccoli: For some pops of vibrant green color and added nutrition.
  • Cheddar Bay Biscuit Mix: Any biscuits will work as a topping, but the cheddar bay biscuits take this casserole to the next level.
  • Milk: whole milk of 2% will work.

How to Make this Chicken and Biscuit Casserole

  • Step 1: In a large oven-safe skillet, melt the butter over medium-high heat.
  • Step 2: Add the garlic and saute for 30 seconds, or until fragrant.
  • Step 3: Whisk in the flour until fully incorporated.
  • Step 4: Pour in half and half, then reduce the heat to medium and simmer for 2 to 3 minutes.
  • Step 5: Whisk in all of your seasonings.
  • Step 6: Mix in grated Parmesan cheese, stirring until smooth.
  • Step 7: Stir in broccoli, cooked chicken, and mozzarella cheese.
  • Step 8: In a separate bowl, combine the biscuit mix with cheddar cheese and milk.
  • Step 9: Drop biscuit mix by the spoonful on top of the chicken mixture.
  • Step 10: Bake at 375 for 25 to 30 minutes, or until golden brown and bubbly. Brush the biscuits with melted butter mixed with the biscuit seasoning packet.

Recipe Tips

  • If your skillet isn’t oven safe, transfer the casserole to a greased 9×13 baking dish.
  • Other vegetables like peas or diced carrots would also work well in this chicken and biscuit casserole.
  • You could even use a bag of frozen mixed vegetables and mix them right into the creamy sauce.
  • Add a little kick of heat with red pepper flakes or chili powder.
A plate of chicken and biscuit casserole.

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